Description

(S)-Azd6738 CAS NO 1352226-87-9 is a high-purity, enantiomerically pure small molecule compound of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in oncology and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced investigational drugs.
• Oncology Research: Used in preclinical and clinical research for developing targeted cancer therapies.
• Biochemical Assay Development: Serves as a reference standard or inhibitor in enzymatic and cellular assays.
• API Development: Critical for process development and scale-up of active pharmaceutical ingredients.
• Academic Research: Utilized in university and institutional labs for mechanistic studies in cell biology and signal transduction.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) libraries to identify new therapeutic leads.

Basic Information

Product Name	(S)-Azd6738
CAS No.	1352226-87-9
Molecular Formula	C₂₁H₂₃N₅O₃
Molecular Weight	393.44 g/mol
Synonyms	(S)-AZD6738; AZD6738 (S-enantiomer); (S)-Ceralasertib; (8S)-8-(6-Amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-8-azaspiro[4.5]decan-1-amine; ATMi (S-enantiomer); ATR Inhibitor (S-form); UNII-Contact for details
EINECS	Contact for details

Quality Control

Every batch of (S)-Azd6738 is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with industry standards for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.