Description

(5-Fluoro-2-Methyl-3-Nitrophenyl)Methanol is a versatile fluorinated aromatic building block with a nitrophenyl core and a hydroxymethyl functional group. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where its structure allows for precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated organic semiconductors and advanced display materials due to its aromatic and polarizable structure.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Functional Group Transformation: The hydroxymethyl group can be readily oxidized to an aldehyde or carboxylic acid, or used to introduce other linkers for polymer and dendrimer synthesis.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	(5-Fluoro-2-Methyl-3-Nitrophenyl)Methanol
CAS No.	1352127-23-1
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	(5-Fluoro-2-methyl-3-nitrophenyl)methanol; 3-Nitro-5-fluoro-2-methylbenzyl alcohol; 5-Fluoro-2-methyl-3-nitrobenzenemethanol; 1-(5-Fluoro-2-methyl-3-nitrophenyl)methanol; (3-Nitro-5-fluoro-2-methylphenyl)methanol; Benzenemethanol, 5-fluoro-2-methyl-3-nitro-; 1352127-23-1
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-Methyl-3-Nitrophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.