Description

[4-[[5-Chloro-4-(Methylamino)-2-Pyrimidinyl]Amino]-3-Methoxyphenyl]-4-Morpholinylmethanone CAS NO 1351758-81-0 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in modern medicinal chemistry for the research and development of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing novel drug candidates, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the discovery and development of potential anti-cancer therapeutics due to its specific pyrimidine-based scaffold.
• Medicinal Chemistry: Serves as a crucial precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Biochemical Research: Employed as a reference standard or a probe compound in enzymatic assays and biological target studies.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	[4-[[5-Chloro-4-(Methylamino)-2-Pyrimidinyl]Amino]-3-Methoxyphenyl]-4-Morpholinylmethanone
CAS No.	1351758-81-0
Molecular Formula	C18H21ClN6O3
Molecular Weight	404.85 g/mol
Synonyms	4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxy-N-morpholinobenzamide; 4-Morpholinyl[4-[[5-chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]methanone; UNII-3Q0U4V8F4G; 3Q0U4V8F4G; Benzamide, 4-((5-chloro-4-(methylamino)-2-pyrimidinyl)amino)-3-methoxy-N-morpholino-; 4-{[5-Chloro-4-(methylamino)pyrimidin-2-yl]amino}-3-methoxy-N-(morpholin-4-yl)benzamide
EINECS	Contact for details

Quality Control

Our [4-[[5-Chloro-4-(Methylamino)-2-Pyrimidinyl]Amino]-3-Methoxyphenyl]-4-Morpholinylmethanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR, MS), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.