Description

3-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is a high-value, heterocyclic building block essential for advanced organic synthesis. Its core value lies in its bifunctional reactivity, offering both a chloro-substituted pyrazolopyridine scaffold and an aldehyde group for further derivatization. This compound is critically needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in kinase inhibitor and pesticide discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, especially kinase inhibitors targeting various cancers and inflammatory diseases.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology: Serves as a versatile probe or linker in the design of chemical tools for studying biological pathways and protein interactions.
• Material Science: Potential building block for creating novel organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, nitrogen-rich structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde
CAS No.	1351613-88-1
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	3-Chloro-1H-pyrazolo[3,4-b]pyridine-5-carboxaldehyde; 3-Chloro-5-formyl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-5-carboxaldehyde, 3-chloro-; 1351613-88-1; 3-Chloro-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 3-Chloro-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (CAS 1351613-88-1)
EINECS	Contact for details

Quality Control

Our 3-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is manufactured under strict quality management systems. We provide material with typical purity grades suitable for research and development, supported by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical grade, higher purity available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.