Description

4-Chloro-3,5-Difluoropicolinaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Building block for synthesizing novel organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for proprietary research and scale-up projects.

Basic Information

Product Name	4-Chloro-3,5-Difluoropicolinaldehyde
CAS No.	1350648-44-0
Molecular Formula	C7H2ClF2NO
Molecular Weight	191.55 g/mol
Synonyms	4-Chloro-3,5-difluoropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 4-chloro-3,5-difluoro-; 4-Chloro-3,5-difluoro-2-formylpyridine; 4-Chloro-3,5-difluoropicolinaldehyde; 1350648-44-0; 4-Chloro-3,5-difluoropyridine-2-carboxaldehyde; Picolinaldehyde, 4-chloro-3,5-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3,5-Difluoropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) when appropriate for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.