Description

3,5-Difluoro-4-Iodo-Pyridine-2-Carbonitrile is a high-value, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique reactivity profile, where the iodine and fluorine substituents enable selective cross-coupling and functional group transformations. It is primarily needed by pharmaceutical, agrochemical, and material science R&D teams for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Fluorinated Compound Libraries: A valuable starting material for generating diverse fluorinated compound libraries for high-throughput screening.

Basic Information

Product Name	3,5-Difluoro-4-Iodo-Pyridine-2-Carbonitrile
CAS No.	1350648-40-6
Molecular Formula	C6HF2IN2
Molecular Weight	265.98 g/mol
Synonyms	4-Iodo-3,5-difluoropyridine-2-carbonitrile; 2-Cyano-3,5-difluoro-4-iodopyridine; 3,5-Difluoro-4-iodo-2-pyridinecarbonitrile; 1350648-40-6; 4-Iodo-3,5-difluoro-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Iodo-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.