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3-Methyl-2-(2-Methylpiperidin-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1350639-17-6
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CAS No.:1350639-17-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Methyl-2-(2-Methylpiperidin-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a sophisticated, multi-functional heterocyclic compound that serves as a critical building block in modern synthetic chemistry. Its value lies in the strategic combination of a pyridine core, a piperidine substituent, and a pinacol boronate ester group, enabling complex molecular construction. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.
Application
- Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl motifs found in drug candidates targeting CNS disorders, oncology, and inflammation.
- Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require complex, nitrogen-containing heterocyclic structures.
- Material Science Research: Serves as a functional monomer or ligand precursor in the creation of advanced polymers, metal-organic frameworks (MOFs), and organic electronic materials.
- Chemical Biology & Probe Development: Employed to synthesize molecular probes and tags for studying biological pathways and protein interactions due to its boronic acid ester functionality.
- Catalyst Ligand Development: The piperidine and pyridine moieties can be utilized to develop novel chiral or non-chiral ligands for asymmetric catalysis and transition metal complexes.
- Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.
Basic Information
| Product Name | 3-Methyl-2-(2-Methylpiperidin-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine |
| CAS No. | 1350639-17-6 |
| Molecular Formula | C18H29BN2O2 |
| Molecular Weight | 316.25 g/mol |
| Synonyms | 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-2-(2-methyl-1-piperidinyl)pyridine; 2-(2-Methylpiperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylpyridine; 3-Methyl-2-(2-methylpiperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol [3-Methyl-2-(2-methyl-1-piperidinyl)-5-pyridyl]boronate; Boronic acid, B-[3-methyl-2-(2-methyl-1-piperidinyl)-5-pyridinyl]-, pinacol ester; CAS 1350639-17-6 |
| EINECS | Contact for details |
Quality Control
Every batch of 3-Methyl-2-(2-Methylpiperidin-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency that meets the exacting standards of pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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