Description

5-Fluoro-4-Iodo-Pyridin-3-Ylamine is a halogenated pyridine derivative, a high-value chemical intermediate prized for its unique reactivity profile. Its structure, featuring both fluorine and iodine substituents on an amine-functionalized pyridine ring, makes it a critical building block for the synthesis of complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized pyridine scaffolds.

Basic Information

Product Name	5-Fluoro-4-Iodo-Pyridin-3-Ylamine
CAS No.	1350475-29-4
Molecular Formula	C5H4FIN2
Molecular Weight	253.00 g/mol
Synonyms	3-Amino-5-fluoro-4-iodopyridine; 4-Iodo-5-fluoropyridin-3-amine; 5-Fluoro-4-iodo-3-pyridinamine; 5-Fluoro-4-iodopyridin-3-amine; 3-Pyridinamine, 5-fluoro-4-iodo-; 1350475-29-4; 5-F-4-I-3-AP
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Iodo-Pyridin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specifications. Our commitment to cGMP standards and rigorous impurity profiling ensures a reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.