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6-(Oxetan-3-Yloxy)Pyridin-3-Amine CAS NO 1349716-84-2


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CAS No.:1349716-84-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(Oxetan-3-Yloxy)Pyridin-3-Amine is a high-purity pharmaceutical intermediate featuring a unique oxetane-pyridine hybrid scaffold. This compound is valued for its role as a versatile building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly in oncology and central nervous system (CNS) disease research.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
  • Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR).
  • Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
  • Kinase Inhibitor Synthesis: Employed in the creation of novel kinase inhibitors due to the privileged pyridine-amine structure.
  • Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name 6-(Oxetan-3-Yloxy)Pyridin-3-Amine
CAS No. 1349716-84-2
Molecular Formula C8H10N2O2
Molecular Weight 166.18 g/mol
Synonyms 3-Amino-6-(oxetan-3-yloxy)pyridine; 6-(Oxetan-3-yloxy)pyridin-3-amine; 3-Pyridinamine, 6-(3-oxetanyloxy)-; 6-(Oxetane-3-yloxy)pyridine-3-amine; 6-(3-Oxetanyloxy)-3-pyridinamine; 6-Oxetan-3-yloxy-pyridin-3-ylamine; (6-(Oxetan-3-yloxy)pyridin-3-yl)amine
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Quality Control

Our 6-(Oxetan-3-Yloxy)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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