Description

9-(2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-β-D-Ribofuranosyl)-6-Chloropurine CAS NO 1347118-41-5 is a high-purity nucleoside derivative and a critical synthetic intermediate in modern pharmaceutical chemistry. Its primary value lies in its role as a key building block for the synthesis of novel antiviral and anticancer nucleotide analogs, enabling the development of targeted therapies. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and biotechnology sectors focused on nucleoside-based drug discovery.

Application

• Pharmaceutical Intermediate: A vital precursor in the multi-step synthesis of modified nucleoside analogs for therapeutic applications.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in studies investigating enzyme mechanisms, such as those of kinases and polymerases, that utilize nucleoside substrates.
• Process Development & Scale-up: Used by process chemists to optimize synthetic routes for the commercial manufacturing of nucleotide drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific novel chemical entities.

Basic Information

Product Name	9-(2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-β-D-Ribofuranosyl)-6-Chloropurine
CAS No.	1347118-41-5
Molecular Formula	C21H19ClN4O6
Molecular Weight	458.85 g/mol
Synonyms	6-Chloro-9-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)purine; 9-(2-O-Acetyl-5-O-benzoyl-3-deoxy-β-D-ribofuranosyl)-6-chloropurine; 6-Chloropurine riboside derivative; 3'-Deoxy-2',5'-di-O-acyl-6-chloropurine nucleoside; 2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-6-chloropurine riboside; 6-Cl-purine nucleoside intermediate; 9-(2-Acetyl-5-benzoyl-3-deoxy-β-D-ribofuranosyl)-6-chloropurine
EINECS	Contact for details

Quality Control

Our 9-(2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-β-D-Ribofuranosyl)-6-Chloropurine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.