Description

(4-Amino-2,5-Difluoro-Phenyl)-Methanol is a versatile aromatic amine derivative featuring both amino and hydroxymethyl functional groups on a difluorinated benzene ring. This unique molecular structure makes it a valuable and highly functionalized building block for advanced organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and polar functional groups.
• Fluorinated Compound Library: An essential component for building diverse screening libraries in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	(4-Amino-2,5-Difluoro-Phenyl)-Methanol
CAS No.	1346764-06-4
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	4-Amino-2,5-difluorobenzyl alcohol; (4-Amino-2,5-difluorophenyl)methanol; 2,5-Difluoro-4-(hydroxymethyl)aniline; 4-(Hydroxymethyl)-2,5-difluoroaniline; 2,5-Difluoro-4-aminobenzyl alcohol; Benzenemethanol, 4-amino-2,5-difluoro-; 4-Amino-2,5-difluorophenylmethanol
EINECS	Contact for details

Quality Control

Every batch of (4-Amino-2,5-Difluoro-Phenyl)-Methanol is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.