Description

7-(1-Methyl-2-Hydroxyethyl)Guanine is a high-purity guanine derivative, a crucial nucleobase analog used in advanced pharmaceutical research and synthesis. This compound serves as a key synthetic intermediate and building block for the development of novel antiviral and anticancer agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on nucleoside chemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs and prodrugs with potential antiviral or anticancer activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modify the guanine scaffold for improved drug efficacy and selectivity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid synthesis pathways.
• Fine Chemical Synthesis: Serves as a specialized starting material for the custom synthesis of labeled compounds or more complex molecular architectures.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry and bioorganic chemistry.

Basic Information

Product Name	7-(1-Methyl-2-Hydroxyethyl)Guanine
CAS No.	1346603-33-5
Molecular Formula	C8H11N5O2
Molecular Weight	209.21 g/mol
Synonyms	7-(1-Methyl-2-hydroxyethyl)guanine; 7-(2-Hydroxy-1-methylethyl)guanine; 7-(1-Hydroxymethylethyl)guanine; Guanine, 7-(1-methyl-2-hydroxyethyl)-; 7-(1-Methyl-2-hydroxyethyl)-1H-purin-6-amine; 7-(1-Methyl-2-hydroxyethyl)-6-aminopurine
EINECS	Contact for details

Quality Control

Our 7-(1-Methyl-2-Hydroxyethyl)Guanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.