Description

5-Bromo-2-(ethylamino)nicotinonitrile is a versatile and high-value pharmaceutical intermediate and organic building block. This compound is crucial for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in developing novel therapeutic agents, especially kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a critical building block for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and production of kinase inhibitors, a major class of targeted cancer therapies.
• Organic Synthesis: Employed as a versatile reagent for introducing functionalized pyridine moieties into more complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of novel pesticides and herbicides.
• Material Science: Can be investigated as a monomer or precursor for functional polymers and advanced materials.

Basic Information

Product Name	5-Bromo-2-(ethylamino)nicotinonitrile
CAS No.	1346541-88-5
Molecular Formula	C8H8BrN3
Molecular Weight	226.08 g/mol
Synonyms	5-Bromo-2-(ethylamino)nicotinonitrile; 5-Bromo-2-(ethylamino)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 5-bromo-2-(ethylamino)-; 2-(Ethylamino)-5-bromonicotinonitrile; 5-Bromo-2-(ethylamino)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(ethylamino)nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere if opened for prolonged use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.