Description

6-Bromo-5-Hydroxy-4-Iodopicolinaldehyde is a highly functionalized pyridine derivative, serving as a sophisticated and versatile building block in advanced organic synthesis. Its unique halogenated and aldehyde-substituted structure makes it a critical intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: A building block for synthesizing functionalized polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.

Basic Information

Product Name	6-Bromo-5-Hydroxy-4-Iodopicolinaldehyde
CAS No.	1346447-15-1
Molecular Formula	C7H3BrINO2
Molecular Weight	339.91 g/mol
Synonyms	4-Iodo-6-bromo-5-hydroxypicolinaldehyde; 5-Hydroxy-6-bromo-4-iodopyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 6-bromo-5-hydroxy-4-iodo-; 6-Bromo-5-hydroxy-4-iodo-2-pyridinecarboxaldehyde; 6-Bromo-5-hydroxy-4-iodopyridine-2-carbaldehyde; 4-Iodo-6-bromo-5-hydroxy-2-formylpyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality control includes identification by spectroscopic methods (NMR, IR), purity assessment by HPLC, and control of key impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request. We support development and cGMP manufacturing needs with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and may be hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.