Description

(7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused dioxino-pyridine structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

This specialized intermediate is designed for high-value synthesis applications, particularly in the pharmaceutical sector. Its primary and potential uses include:

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Development: Serves as a core scaffold for constructing active pharmaceutical ingredients targeting various disease pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	(7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Methanol
CAS No.	1346447-14-0
Molecular Formula	C9H8ClNO3
Molecular Weight	213.62 g/mol
Synonyms	8-(Hydroxymethyl)-7-chloro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; 7-Chloro-2,3-dihydro-1,4-dioxino[2,3-b]pyridine-8-methanol; (7-Chloro-2,3-dihydro-1,4-dioxino[2,3-b]pyridin-8-yl)methanol; 1346447-14-0; 7-Chloro-8-(hydroxymethyl)-2,3-dihydro-1,4-dioxino[2,3-b]pyridine
EINECS	Contact for details

Quality Control

We supply (7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-8-Yl)Methanol to meet the stringent requirements of pharmaceutical R&D and production. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. Quality management is supported by our commitment to cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored in a cool, dry place. For long-term stability, store at 2-8°C under an inert atmosphere such as nitrogen or argon. Keep the container tightly sealed in a desiccator to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.