Description

3-(1H-Pyrazolo[3,4-B]Pyridin-5-Yl)Propan-1-Ol is a high-purity organic building block and pharmaceutical intermediate of significant interest in modern drug discovery. Its molecular structure, featuring a fused pyrazolopyridine core, makes it a valuable scaffold for synthesizing novel bioactive compounds targeting various therapeutic areas. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics. We supply this critical intermediate with a focus on consistent quality, reliable purity, and secure global logistics to support advanced R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound Development: Employed in the creation of probes and ligands for studying specific enzyme targets and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug design.
• Preclinical Candidate Synthesis: Integrated into the synthetic route for developing lead optimization candidates and preclinical materials.

Basic Information

Product Name	3-(1H-Pyrazolo[3,4-B]Pyridin-5-Yl)Propan-1-Ol
CAS No.	1346447-07-1
Molecular Formula	C9H11N3O
Molecular Weight	177.20 g/mol
Synonyms	5-(3-Hydroxypropyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridin-5-propanol; 3-(1H-Pyrazolo[3,4-b]pyridin-5-yl)-1-propanol; 3-(1H-Pyrazolo[3,4-B]Pyridin-5-Yl)Propanol; 5-(3-Hydroxypropyl)pyrazolo[3,4-b]pyridine; 1346447-07-1; Pyrazolopyridine propanol derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(1H-Pyrazolo[3,4-B]Pyridin-5-Yl)Propan-1-Ol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.