Description

tert-Butyl (6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridin-8-Yl)Carbamate is a high-value, heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Serves as a probe or precursor for labeling studies due to the reactive iodine moiety.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: Starting material for the contract manufacturing of specialized, high-purity compounds for clinical trials.

Basic Information

Product Name	tert-Butyl (6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridin-8-Yl)Carbamate
CAS No.	1346447-06-0
Molecular Formula	C13H17IN2O3
Molecular Weight	376.19 g/mol
Synonyms	8-[(tert-Butoxycarbonyl)amino]-6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine; 6-Iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridin-8-amine, N-BOC-protected; tert-Butyl 6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridin-8-ylcarbamate; BOC-6-Iodo-DHPP; 6-Iodo-DHPP-BOC; 1346447-06-0; tert-Butyl (6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridin-8-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridin-8-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.