Description

(1R)-1-(3-Chloro-4-Fluorophenyl)Ethan-1-Ol CAS NO 1344913-01-4 is a high-purity chiral alcohol intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical industries who require a reliable source of a specific stereoisomer for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, optically active pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a high degree of stereochemical control.
• Academic and Industrial R&D: A valuable reagent for method development and exploration of new synthetic routes in organic chemistry research.

Basic Information

Product Name	(1R)-1-(3-Chloro-4-Fluorophenyl)Ethan-1-Ol
CAS No.	1344913-01-4
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	(R)-1-(3-Chloro-4-fluorophenyl)ethanol; (1R)-1-(3-Chloro-4-fluorophenyl)ethanol; (R)-3-Chloro-4-fluoro-α-methylbenzyl alcohol; (R)-α-Methyl-3-chloro-4-fluorobenzyl alcohol; (R)-1-(3-Chloro-4-fluorophenyl)ethyl alcohol; (R)-(-)-1-(3-Chloro-4-fluorophenyl)ethanol; (R)-CFP-EtOH; 1344913-01-4
EINECS	Contact for details

Quality Control

Our production of (1R)-1-(3-Chloro-4-Fluorophenyl)Ethan-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.