Description

5-Bromo-2-Chlorophenylisothiocyanate is a versatile and highly reactive organic building block used in advanced chemical synthesis. Its value lies in the isothiocyanate functional group, which readily reacts with amines to form thiourea derivatives, a key step in creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Chemical Biology Probe Development: Employed to create affinity-based probes for studying protein function and identifying drug targets within biological systems.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Ligand Synthesis for Catalysis: Utilized to prepare novel thiourea-based ligands for asymmetric catalysis and metal complexation.

Basic Information

Product Name	5-Bromo-2-Chlorophenylisothiocyanate
CAS No.	1344298-28-7
Molecular Formula	C7H3BrClNS
Molecular Weight	248.53 g/mol
Synonyms	2-Chloro-5-bromophenyl isothiocyanate; 1-Bromo-4-chloro-2-isothiocyanatobenzene; (5-Bromo-2-chlorophenyl)isothiocyanate; 5-Bromo-2-chlorobenzene isothiocyanate; Isothiocyanic acid, 5-bromo-2-chlorophenyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chlorophenylisothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.