Description

1-(3-Fluoropyridin-2-Yl)-3-Oxocyclobutane-1-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane and fluoropyridine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its specific molecular framework into new compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new generation pesticides and herbicides with enhanced efficacy.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Ligand and Catalyst Development: Potential use in creating novel ligands for catalytic systems or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(3-Fluoropyridin-2-Yl)-3-Oxocyclobutane-1-Carbonitrile
CAS No.	1344145-36-3
Molecular Formula	C10H7FN2O
Molecular Weight	190.18 g/mol
Synonyms	3-Oxo-1-(3-fluoropyridin-2-yl)cyclobutane-1-carbonitrile; 1-(3-Fluoro-2-pyridinyl)-3-oxocyclobutanecarbonitrile; 3-Oxo-1-(3-fluoropyridin-2-yl)cyclobutanecarbonitrile; 1-(3-Fluoropyridin-2-yl)-3-oxocyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(3-fluoro-2-pyridinyl)-3-oxo-; 1344145-36-3
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoropyridin-2-Yl)-3-Oxocyclobutane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.