Description

1-(3-Chloro-2-Fluorophenyl)Propan-1-Ol is a high-purity fluorinated aromatic alcohol building block of significant importance in advanced organic synthesis. This compound serves as a critical chiral intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated phenylpropanol structure enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides and fungicides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated components for liquid crystal displays (LCDs) due to its aromatic and polar properties.
• Organic Electronic Materials: Serves as a starting material for synthesizing charge-transport or emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile reagent for method development, asymmetric synthesis, and exploring new reaction pathways in academic and industrial R&D labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)Propan-1-Ol
CAS No.	1343664-57-2
Molecular Formula	C9H10ClFO
Molecular Weight	188.63 g/mol
Synonyms	1-(3-Chloro-2-fluorophenyl)-1-propanol; 3-Chloro-2-fluorophenyl propanol; 1-Propanol, 1-(3-chloro-2-fluorophenyl)-; (3-Chloro-2-fluorophenyl)propan-1-ol; α-Ethyl-3-chloro-2-fluorobenzyl alcohol; 3-Chloro-2-fluoro-α-ethylbenzyl alcohol; 1-(3-Chloro-2-fluorophenyl)propanol; 1343664-57-2
EINECS	Contact for details

Quality Control

Our production of 1-(3-Chloro-2-Fluorophenyl)Propan-1-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical and advanced material applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects with material produced under quality systems aligned with ISO and cGMP principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.