Description

1-(6-Chloro-Pyridin-3-Ylmethyl)-Pyrrolidin-3-Ol is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical center. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective therapeutics. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates targeting neurological disorders.
• Agrochemical Research: Used in the development of new-generation insecticides and pesticides with specific modes of action.
• Chemical Biology: Serves as a versatile scaffold or ligand in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in route scouting and optimization for scalable API manufacturing processes.
• Reference Standard: Utilized as an analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	1-(6-Chloro-Pyridin-3-Ylmethyl)-Pyrrolidin-3-Ol
CAS No.	1343606-51-8
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	3-Pyrrolidinol, 1-[(6-chloro-3-pyridinyl)methyl]-; (3R)-1-[(6-Chloropyridin-3-yl)methyl]pyrrolidin-3-ol; (S)-1-((6-Chloropyridin-3-yl)methyl)pyrrolidin-3-ol; 1-[(6-Chloro-3-pyridinyl)methyl]-3-pyrrolidinol; 1-(6-Chloro-3-pyridylmethyl)pyrrolidin-3-ol; 1-(6-Chloropyridin-3-ylmethyl)pyrrolidin-3-ol; Pyrrolidin-3-ol, 1-[(6-chloro-3-pyridinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-Pyridin-3-Ylmethyl)-Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.