Description

7Methyl-5-(1-{[3-(Trifluoromethyl)Phenyl]Acetyl}-2,3-Dihydro1Hindol-5-Yl)7Hpyrrolo[2,3D]Pyrimidin-4-Amine is a sophisticated heterocyclic organic compound featuring a pyrrolo[2,3-d]pyrimidine core, a key structural motif in medicinal chemistry. This compound matters as a high-value pharmaceutical intermediate or active pharmaceutical ingredient (API) precursor, designed for targeted therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of novel small-molecule drugs, particularly in oncology and kinase-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors due to its privileged pyrrolopyrimidine scaffold.
• Oncology Drug Discovery: Acts as a key precursor in the synthesis of compounds targeting specific cancer cell pathways.
• Biochemical Research: Employed as a reference standard or probe molecule in biochemical and pharmacological assays.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for studying structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	7Methyl-5-(1-{[3-(Trifluoromethyl)Phenyl]Acetyl}-2,3-Dihydro1Hindol-5-Yl)7Hpyrrolo[2,3D]Pyrimidin-4-Amine
CAS No.	1337531-36-8
Molecular Formula	C24H20F3N5O
Molecular Weight	451.45 g/mol
Synonyms	7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-methyl-5-[1-[[3-(trifluoromethyl)phenyl]carbonyl]-2,3-dihydro-1H-indol-5-yl]-; CAS 1337531-36-8; 1337531-36-8; 7-Methyl-5-(1-(3-(trifluoromethyl)benzoyl)indolin-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 7Methyl-5-(1-{[3-(Trifluoromethyl)Phenyl]Acetyl}-2,3-Dihydro1Hindol-5-Yl)7Hpyrrolo[2,3D]Pyrimidin-4-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.