Description

2'-B-C-Methyl-2-Amino-N6,N6-Dimethyladenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for novel antiviral and anticancer therapeutics, particularly targeting RNA-dependent processes. It is primarily needed by research institutions, biotechnology firms, and pharmaceutical companies engaged in the discovery of nucleoside-based drugs, where precise chemical structure and high purity are critical for biological activity and regulatory approval. The compound is supplied to meet the stringent requirements of modern medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA polymerase mechanisms and nucleotide metabolism.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Antiviral Drug Development: Investigated for potential activity against viruses such as hepatitis C virus (HCV) and other RNA viruses due to its 2'-C-methyl modification.
• Preclinical Studies: Utilized in in vitro and in vivo models to assess pharmacokinetics, efficacy, and toxicity profiles.
• Process Chemistry & Scale-up: Acts as a reference standard or starting material for developing robust, scalable synthetic routes under GMP conditions.

Basic Information

Product Name	2'-B-C-Methyl-2-Amino-N6,N6-Dimethyladenosine
CAS No.	1336975-57-5
Molecular Formula	C13H19N7O4
Molecular Weight	337.34 g/mol
Synonyms	2'-C-Methyl-2-amino-N6,N6-dimethyladenosine; 2'-C-Methyl-2-amino-N(6),N(6)-dimethyladenosine; 2-Amino-2'-C-methyl-N6,N6-dimethyladenosine; 2'-C-Methyl-2,6-diaminopurine riboside derivative; N6,N6-Dimethyl-2-amino-2'-C-methyladenosine; 2'-Methyl-2-aminoadenosine N6,N6-dimethyl derivative; 1336975-57-5; Adenosine, 2-amino-2-C-methyl-N6,N6-dimethyl-
EINECS	Contact for details

Quality Control

Our 2'-B-C-Methyl-2-Amino-N6,N6-Dimethyladenosine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Quality assurance includes comprehensive analytical testing via HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch. We support development from milligram to kilogram scale with documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.