Description

n-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester is a high-purity, chiral organophosphorus compound designed for advanced synthetic applications. This specialty chemical serves as a critical building block or intermediate in the development of novel active ingredients, where its unique stereochemistry and functional groups enable precise molecular construction. It is primarily utilized by research and development teams within the pharmaceutical and agrochemical industries for creating new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, insecticides, and fungicides, leveraging its phosphinyl and pentafluorophenoxy motifs.
• Chemical Biology Probe: Serves as a precursor for designing enzyme inhibitors or activity-based probes to study biological pathways.
• Asymmetric Synthesis: Employed as a reagent or ligand precursor in catalytic asymmetric transformations due to its defined (S)-configuration.
• Material Science Research: Potential intermediate for synthesizing specialized polymers or ligands with specific electronic properties.

Basic Information

Item	Details
Product Name	n-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester
CAS No.	1334513-02-8
Molecular Formula	C18H16F5NO5P
Molecular Weight	461.29 g/mol
Synonyms	(S)-Isopropyl 2-(((2,3,4,5,6-Pentafluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; L-Alanine, N-[(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester, (S)-; Isopropyl (S)-2-((phenoxy(2,3,4,5,6-pentafluorophenoxy)phosphoryl)amino)propanoate; Pentafluorophenyl phenyl phosphoramidate-L-alanine isopropyl ester; Chiral organophosphorus amide ester
EINECS	Contact for details

Quality Control

Every batch of n-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.