Description

6-Nitro-8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and anti-infective drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of new chemical entities.
• API Synthesis: Serves as a precursor in the production of active pharmaceutical ingredients for preclinical and clinical development.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	6-Nitro-8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide
CAS No.	1332605-92-1
Molecular Formula	C11H9BrN3O4 • HBr
Molecular Weight	392.03 g/mol (for the hydrobromide salt)
Synonyms	Ethyl 6-Nitro-8-Bromoimidazo[1,2-a]pyridine-2-carboxylate Hydrobromide; 8-Bromo-6-nitroimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester Hydrobromide; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-6-nitro-, ethyl ester, hydrobromide; 1332605-92-1; 6-Nitro-8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester HBr salt
EINECS	Contact for details

Quality Control

Our 6-Nitro-8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in their regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.