Description

(Pyridin-2-Ylthio)Acetyl Chloride Hydrochloride is a high-purity, reactive chemical building block primarily used in advanced pharmaceutical synthesis and organic research. Its core value lies in its role as a versatile acylating agent, enabling the efficient introduction of the (pyridin-2-ylthio)acetyl moiety into target molecules. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific biological activity.
• Chemical Biology & Proteomics: Serves as a reagent for modifying proteins or peptides, useful in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Material Science Research: Employed in the creation of functionalized polymers or organic electronic materials that incorporate pyridine-thioether motifs.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers offering bespoke synthesis services for complex organic molecules.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic chemistry and exploration of new reaction pathways.

Basic Information

Item	Detail
Product Name	(Pyridin-2-Ylthio)Acetyl Chloride Hydrochloride
CAS No.	1332531-12-0
Molecular Formula	C7H7Cl2NOS
Molecular Weight	224.11 g/mol
Synonyms	2-((Pyridin-2-ylthio)acetyl chloride hydrochloride; 2-(Pyridin-2-ylsulfanyl)acetyl chloride hydrochloride; (2-Pyridylthio)acetyl Chloride Hydrochloride; α-Chloro-2-pyridylthioacetone Hydrochloride (common misnomer); Pyridine-2-thiol acetic acid chloride hydrochloride; 2-Pyridylthioacetyl chloride HCl; (Pyridin-2-ylthio)acetic acid chloride hydrochloride
EINECS	Contact for details

Quality Control

Our (Pyridin-2-Ylthio)Acetyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and cGMP-intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.