Description

6-(Acetoxymethyl)-4-Methoxy-5-Methyl-Nicotinic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry: Employed in route scouting and optimization for scalable, cost-effective manufacturing of target compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and biochemical research.

Basic Information

Product Name	6-(Acetoxymethyl)-4-Methoxy-5-Methyl-Nicotinic Acid Methyl Ester
CAS No.	1329633-58-0
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	Methyl 6-(acetoxymethyl)-4-methoxy-5-methylnicotinate; 4-Methoxy-5-methyl-6-(acetoxymethyl)nicotinic acid methyl ester; Methyl 4-methoxy-5-methyl-6-(acetoxymethyl)pyridine-3-carboxylate; Nicotinic acid, 6-(acetoxymethyl)-4-methoxy-5-methyl-, methyl ester; CAS 1329633-58-0
EINECS	Contact for details

Quality Control

Our 6-(Acetoxymethyl)-4-Methoxy-5-Methyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.