Description

5-((5-(Trifluoromethyl)Pyridin-2-Yl)Oxy)Thiazol-2-Amine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethylpyridine and aminothiazole motifs confer desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas such as oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and trifluoromethylpyridine scaffolds.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and protein function.
• Material Science Research: Potential precursor for the synthesis of specialty polymers, ligands for catalysis, or advanced materials with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	5-((5-(Trifluoromethyl)Pyridin-2-Yl)Oxy)Thiazol-2-Amine
CAS No.	1328998-37-3
Molecular Formula	C9H6F3N3OS
Molecular Weight	261.22 g/mol
Synonyms	2-Amino-5-[(5-(trifluoromethyl)-2-pyridinyl)oxy]-1,3-thiazole; 2-Amino-5-((5-(trifluoromethyl)pyridin-2-yl)oxy)thiazole; 5-((5-(Trifluoromethyl)-2-pyridyl)oxy)-2-aminothiazole; 2-Pyridinol, 5-(trifluoromethyl)-, 2-aminothiazol-5-yl ether; Thiazol-2-amine, 5-((5-(trifluoromethyl)-2-pyridinyl)oxy)-; CAS 1328998-37-3
EINECS	Contact for details

Quality Control

Our 5-((5-(Trifluoromethyl)Pyridin-2-Yl)Oxy)Thiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material suitable for research use, process development, and can discuss cGMP-grade manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.