Description

4-Chloro-2-Fluoro-3-Methoxybenzoyl Chloride, 97% is a high-purity, multi-functional aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive benzoyl chloride group and strategically placed halogen and methoxy substituents, enabling precise molecular construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-quality reagent for developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro-methoxy substitution pattern contributes to biological activity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating complex aromatic cores in electronic and display materials, where specific halogenation is crucial for electronic properties.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, including high-performance polyamides and polyesters.
• Dye & Pigment Manufacturing: Intermediate for synthesizing complex azo and anthraquinone-based dyes and pigments with enhanced lightfastness and color properties.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create biaryl structures common in many advanced materials.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methoxybenzoyl Chloride, 97%
CAS No.	1323966-24-0
Molecular Formula	C8H5Cl2FO2
Molecular Weight	223.03 g/mol
Synonyms	4-Chloro-2-fluoro-3-methoxybenzoic acid chloride; 3-Methoxy-4-chloro-2-fluorobenzoyl chloride; 2-Fluoro-3-methoxy-4-chlorobenzoyl chloride; Benzoyl chloride, 4-chloro-2-fluoro-3-methoxy-; 1323966-24-0; 4-Chloro-2-fluoro-3-methoxy-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-3-Methoxybenzoyl Chloride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the specified 97% minimum purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, it should be stored separately from bases, amines, and oxidizing agents. Containers must be kept tightly sealed to exclude moisture from the air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.