Description

2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzoyl Chloride, 97% is a high-purity, multi-functional aromatic acid chloride building block essential for advanced organic synthesis. This compound is valued for its unique trifluoromethyl and fluorine substituents, which impart desirable electronic and steric properties to target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorinated benzoyl groups into polymer chains, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to construct complex fluorinated aromatic ketones and amides.
• Chemical Research & Development: Essential for medicinal chemistry and material science R&D programs exploring structure-activity relationships (SAR) of fluorinated compounds.

Basic Information

Product Name	2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzoyl Chloride, 97%
CAS No.	1323966-18-2
Molecular Formula	C9H5ClF4O
Molecular Weight	240.58 g/mol
Synonyms	4-(Trifluoromethyl)-2-fluoro-5-methylbenzoyl chloride; 2-Fluoro-5-methyl-α,α,α-trifluoro-p-toluoyl chloride; 2-Fluoro-α,α,α-trifluoro-5-methyl-p-toluoyl chloride; 2-Fluoro-5-methyl-4-trifluoromethylbenzoyl chloride; 4-(Trifluoromethyl)-2-fluoro-5-methylbenzoic acid chloride; 2-Fluoro-5-methyl-4-(trifluoromethyl)benzenecarbonyl chloride; Benzoyl chloride, 2-fluoro-5-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methyl-4-(Trifluoromethyl)Benzoyl Chloride, 97% is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the specified standards. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Due to its reactivity as an acid chloride and sensitivity to moisture, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.