Description

Cardenolide B-1 CAS NO 1318158-89-2 is a high-purity, specialized cardenolide compound of significant interest in pharmaceutical research and development. This compound serves as a critical reference standard and building block for the synthesis of novel therapeutic agents targeting cardiovascular and oncological pathways. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: For the qualitative and quantitative analysis (HPLC, LC-MS) of cardenolide-based drug substances and products.
• Drug Discovery & Medicinal Chemistry: As a key intermediate or pharmacophore for synthesizing new chemical entities with potential cardiotonic or anticancer activity.
• Biochemical Research: Used in studies to investigate the mechanism of action of Na+/K+-ATPase inhibition and its downstream cellular effects.
• Impurity Profiling: Serves as an identified impurity standard in the quality control of related steroid-based active pharmaceutical ingredients (APIs).
• Academic Research: For pharmacological and toxicological studies in university and institutional laboratories.

Basic Information

Product Name	Cardenolide B-1
CAS No.	1318158-89-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cardenolide B1; (3β,5β,14β)-3,14-Dihydroxy-19-oxocard-20(22)-enolide; 3β,14β-Dihydroxy-19-oxo-5β-card-20(22)-enolide; 19-Oxocardenolide B-1; Cardenolide B1 (CAS 1318158-89-2); 19-Oxo-cardenolide B1
EINECS	Contact for details

Quality Control

Our Cardenolide B-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.