Description

3’-Deoxy-3’-Fluorothymidine-5’-Monophosphate Disodium Salt is a chemically modified nucleoside monophosphate analog, a critical building block in antiviral and anticancer research. This compound matters as a key intermediate for the synthesis of more complex nucleotide prodrugs, enabling the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on virology and oncology.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced nucleotide analogs for antiviral therapies.
• Antiviral Research: Used in biochemical studies targeting viral polymerases, particularly for HIV, HBV, and HCV.
• Oncology Research: Investigated as a potential component in prodrugs designed to inhibit cancer cell proliferation.
• Biochemical Probe: Serves as a tool compound to study nucleotide metabolism and enzyme kinetics in cellular systems.
• Nucleic Acid Chemistry: Employed in the development of modified oligonucleotides for diagnostic and therapeutic applications.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	3’-Deoxy-3’-Fluorothymidine-5’-Monophosphate Disodium Salt
CAS No.	1316845-74-5
Molecular Formula	C10H13FN2Na2O7P
Molecular Weight	376.16 g/mol
Synonyms	FLT-MP Disodium Salt; 3'-Fluoro-3'-deoxythymidine-5'-monophosphate Disodium Salt; Alovudine-5'-monophosphate Disodium Salt; 3'-F-3'-dTMP Disodium; 5'-O-Phosphono-3'-deoxy-3'-fluorothymidine Disodium Salt; 3'-Fluoro-5'-O-phosphonothymidine Disodium Salt; 3'-F-dTMP Na2
EINECS	Contact for details

Quality Control

Our 3’-Deoxy-3’-Fluorothymidine-5’-Monophosphate Disodium Salt is manufactured under strict quality systems suitable for research and development use. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistent quality and reliable performance. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.