Description

Tak-659 is a potent and selective small molecule inhibitor with significant research and development interest. This compound is valued for its targeted mechanism of action, making it a crucial tool for advancing scientific understanding in specific biological pathways. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in drug discovery and preclinical studies. The material is supplied under the identifier CAS NO 1312691-33-0 to ensure precise sourcing and regulatory compliance.

Application

• Biomedical Research: Used as a key reference standard and active pharmaceutical ingredient (API) in pharmacological and biochemical assays.
• Drug Discovery Programs: Serves as a lead compound or tool molecule for investigating specific kinase-related pathways and validating novel therapeutic targets.
• Preclinical Development: Employed in in vitro and in vivo studies to assess efficacy, pharmacokinetics, and safety profiles.
• Chemical Biology: Acts as a selective probe to study protein function and signal transduction mechanisms within cells.
• High-Throughput Screening (HTS): Utilized in assay development and as a control compound in screening libraries to identify new drug candidates.

Basic Information

Product Name	Tak-659
CAS No.	1312691-33-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sapanisertib analog; UNC-569; (S)-N-(5-((2,3-Dihydro-1H-inden-4-yl)oxy)pyridin-3-yl)-1-methyl-1H-pyrazole-5-carboxamide; 5-[[(2S)-2,3-Dihydro-1H-inden-4-yl]oxy]-3-pyridinyl 1-methyl-1H-pyrazole-5-carboxylate; Research Compound 1312691-33-0; Kinase Inhibitor 659; TAK-659 free base
EINECS	Contact for details

Quality Control

Our Tak-659 is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider handling under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.