Description

3-[6-Dimethylamino-4-(Trifluoromethyl)Pyridin-2-Yl]Phenol is a high-value, multi-functional chemical intermediate featuring a unique trifluoromethylpyridine-phenol hybrid structure. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern imparts desirable electronic and steric properties. It is primarily needed by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes for biological imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, functionalized aromatic systems.

Basic Information

Item	Details
Product Name	3-[6-Dimethylamino-4-(Trifluoromethyl)Pyridin-2-Yl]Phenol
CAS No.	1311278-78-0
Molecular Formula	C14H13F3N2O
Molecular Weight	282.26 g/mol
Synonyms	2-Hydroxy-5-[6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl]phenol; 3-(6-(Dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenol; 2-(3-Hydroxyphenyl)-6-(dimethylamino)-4-(trifluoromethyl)pyridine; Phenol, 3-[6-(dimethylamino)-4-(trifluoromethyl)-2-pyridinyl]-; 1311278-78-0
EINECS	Contact for details

Quality Control

Our 3-[6-Dimethylamino-4-(Trifluoromethyl)Pyridin-2-Yl]Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports applications requiring reliable and traceable raw materials for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.