Description

1-Boc-5-(Benzyloxy)-3-Methyl-1H-Pyrazolo[3,4-C]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a protected pyrazolopyridine core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing potent and selective kinase inhibitors due to its privileged heterocyclic architecture.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient and cost-effective manufacturing of complex drug molecules.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services, providing a protected, functionalized handle for further chemical elaboration.

Basic Information

Product Name	1-Boc-5-(Benzyloxy)-3-Methyl-1H-Pyrazolo[3,4-C]Pyridine
CAS No.	1311254-55-3
Molecular Formula	C20H23N3O3
Molecular Weight	353.42 g/mol
Synonyms	1-Boc-5-(benzyloxy)-3-methyl-1H-pyrazolo[3,4-c]pyridine; tert-Butyl 5-(benzyloxy)-3-methyl-1H-pyrazolo[3,4-c]pyridine-1-carboxylate; 1H-Pyrazolo[3,4-c]pyridine-1-carboxylic acid, 5-(benzyloxy)-3-methyl-, 1,1-dimethylethyl ester; 5-Benzyloxy-3-methyl-1H-pyrazolo[3,4-c]pyridine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-(benzyloxy)-3-methyl-1H-pyrazolo[3,4-c]pyridine; Boc-protected 5-benzyloxy-3-methylpyrazolopyridine
EINECS	Contact for details

Quality Control

Our 1-Boc-5-(Benzyloxy)-3-Methyl-1H-Pyrazolo[3,4-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or with appropriate desiccant to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.