Description

Nvp Bgj398 Phosphate CAS NO 1310746-10-1 is a specialized phosphate derivative of a kinase inhibitor intermediate, designed for high-precision pharmaceutical research and development. This compound is critical for advancing targeted cancer therapies, particularly in the development of novel kinase inhibitors. It serves as a key building block for medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors, enabling the synthesis of next-generation therapeutic candidates.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced kinase inhibitor drug candidates.
• Oncology Research: Utilized in preclinical and discovery-stage research for developing targeted cancer therapies.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Biochemical Assay Development: Used as a reference standard or probe compound in high-throughput screening and mechanism-of-action studies.
• Academic Research: Employed in university and institutional labs for studying kinase signaling pathways and drug-target interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry with custom synthesis and development services.

Basic Information

Product Name	Nvp Bgj398 Phosphate
CAS No.	1310746-10-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BGJ398 Phosphate; NVP-BGJ398 phosphate; BGJ 398 phosphate salt; INCB054828 phosphate; Fibroblast Growth Factor Receptor (FGFR) inhibitor phosphate; (3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one) phosphate; INCB 054828 phosphate
EINECS	Contact for details

Quality Control

Our Nvp Bgj398 Phosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable for pharmaceutical intermediates, and our quality commitment ensures material traceability and reliability for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.