Description

Ethyl 5-Chloro-2-Ethoxypyridine-3-Carboxylate is a high-purity pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its specific substitution pattern, which makes it an essential intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and functional dyes due to its electron-deficient heterocyclic structure.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Item	Details
Product Name	Ethyl 5-Chloro-2-Ethoxypyridine-3-Carboxylate
CAS No.	1310416-61-5
Molecular Formula	C10H12ClNO3
Molecular Weight	229.66 g/mol
Synonyms	5-Chloro-2-ethoxy-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-chloro-2-ethoxy-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 5-chloro-2-ethoxy-, ethyl ester; 5-Chloro-2-ethoxynicotinic acid ethyl ester; 2-Ethoxy-5-chloropyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-2-Ethoxypyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all test results are provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.