Description

3-Bromo-2-Methylpyridine-6-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual functionality, serving as a versatile building block for constructing complex heterocyclic molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and R&D Laboratories: Used in exploratory chemistry for developing new synthetic methodologies and discovering novel chemical entities.

Basic Information

Product Name	3-Bromo-2-Methylpyridine-6-Carbonyl Chloride
CAS No.	1310416-51-3
Molecular Formula	C8H7BrClNO
Molecular Weight	248.50 g/mol
Synonyms	6-(Chlorocarbonyl)-3-bromo-2-methylpyridine; 3-Bromo-2-methylpyridine-6-carboxylic acid chloride; 2-Methyl-3-bromopyridine-6-carbonyl chloride; 3-Bromo-2-picolinyl chloride; 3-Bromo-2-methyl-6-pyridinecarbonyl chloride; 6-Carbonyl chloride-3-bromo-2-methylpyridine; (3-Bromo-2-methylpyridin-6-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methylpyridine-6-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.