Description

3-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid is a high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Suzuki-Miyaura Cross-Coupling: Serves as a reliable boronic acid coupling partner for palladium-catalyzed C-C bond formation with aryl/heteroaryl halides.
• Ligand and Catalyst Development: Employed in the creation of novel bidentate ligands and organocatalysts due to its pyridine and boronic acid functional groups.
• Materials Science Research: A building block for constructing conjugated polymers and organic semiconductors used in OLEDs and photovoltaic cells.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	3-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid
CAS No.	1310384-99-6
Molecular Formula	C8H12BNO3
Molecular Weight	180.99 g/mol
Synonyms	2-(2-Hydroxypropan-2-yl)pyridine-3-boronic acid; 3-Borono-2-(2-hydroxy-2-propyl)pyridine; 2-(1-Hydroxy-1-methylethyl)-3-pyridineboronic acid; 3-Pyridineboronic acid, 2-(2-hydroxy-2-propyl)-; (2-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid; 2-(2-Hydroxy-2-propyl)pyridine-3-boronic Acid; 3-Borono-2-(1-hydroxy-1-methylethyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.