Description

2-tert-Butyloxycarbonylamino-3-Nitropyridine-5-Boronic Acid Pinacol Ester CAS NO 1310383-54-0 is a sophisticated, multi-functional chemical building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates for constructing complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for constructing biaryl and heterobiaryl structures, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its nitropyridine and boronate functional groups.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a valuable tool compound for bioconjugation and the development of activity-based probes.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-tert-Butyloxycarbonylamino-3-Nitropyridine-5-Boronic Acid Pinacol Ester
CAS No.	1310383-54-0
Molecular Formula	C16H24BN3O6
Molecular Weight	365.19 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-nitro-N-Boc-pyridin-2-amine; 2-((tert-Butoxycarbonyl)amino)-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-N-Boc-amino-3-nitro-5-pyridineboronic acid pinacol ester; Boc-2-Amino-3-nitro-5-pyridineboronic acid pinacol ester; 3-Nitro-2-((tert-butoxycarbonyl)amino)pyridine-5-boronic acid pinacol ester; 2-(Boc-amino)-3-nitro-5-(pinacolboronato)pyridine; N-Boc-2-amino-3-nitro-5-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-tert-Butyloxycarbonylamino-3-Nitropyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.