Description

(S)-(3-((3-Aminopyridin-4-Ylamino)Methyl)Pyrrolidin-1-Yl)(Cyclopropyl)Methanone CAS NO 1309806-17-4 is a high-purity, chiral pyrrolidine derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is essential for medicinal chemists and process development scientists in pharmaceutical and biotechnology companies who require reliable, high-quality intermediates to accelerate drug discovery and development timelines.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and functional groups.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Synthesis: The aminopyridine moiety can be utilized for creating labeled compounds or conjugates for biological testing and imaging.
• Chemical Biology: Potential use in the development of chemical probes to study specific enzyme or receptor functions.
• Custom Synthesis: Foundation for the custom manufacturing of more complex, proprietary molecules for client-specific R&D programs.

Basic Information

Product Name	(S)-(3-((3-Aminopyridin-4-Ylamino)Methyl)Pyrrolidin-1-Yl)(Cyclopropyl)Methanone
CAS No.	1309806-17-4
Molecular Formula	C15H21N5O
Molecular Weight	287.36 g/mol
Synonyms	(S)-N-(4-Amino-3-pyridinyl)-1-(cyclopropylcarbonyl)-3-pyrrolidinemethanamine; (S)-(3-((3-Amino-4-pyridinyl)amino)methyl)-1-pyrrolidinyl)(cyclopropyl)methanone; (S)-1-(Cyclopropanecarbonyl)-3-[(3-amino-4-pyridylamino)methyl]pyrrolidine; (S)-3-[(3-Amino-4-pyridinylamino)methyl]-1-(cyclopropylcarbonyl)pyrrolidine; Cyclopropyl (S)-[3-[(3-amino-4-pyridinylamino)methyl]-1-pyrrolidinyl]methanone; CAS 1309806-17-4
EINECS	Contact for details

Quality Control

Our (S)-(3-((3-Aminopyridin-4-Ylamino)Methyl)Pyrrolidin-1-Yl)(Cyclopropyl)Methanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral purity, and impurity profiles. Our quality systems are designed to support pharmaceutical development requirements, with the capability to supply material under ICH stability guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.