Description

Poly(Oxy-1,2-Ethanediyl),α-[4-[[3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl]Oxy]-1,4-Dioxobutyl]-ω-Methoxy-Polymer is a specialized polymer derivative of Vitamin E (Tocopherol) conjugated with polyethylene glycol (PEG), designed to enhance the solubility and bioavailability of the antioxidant moiety. This compound matters for formulators seeking to leverage the powerful antioxidant properties of Vitamin E in aqueous-based systems where the native form is poorly soluble. It is primarily needed by manufacturers in the pharmaceutical, nutraceutical, and high-performance cosmetic industries for developing advanced delivery systems and stable formulations.

Application

• Pharmaceutical Drug Delivery: As a solubilizing agent and carrier for lipophilic active pharmaceutical ingredients (APIs) in injectable and oral formulations.
• Advanced Cosmetic Serums & Creams: To incorporate stable, water-soluble Vitamin E antioxidant activity into anti-aging, moisturizing, and protective skincare products.
• Nutraceutical & Functional Food Enhancers: For the development of clear beverages, fortified waters, or gel caps with improved Vitamin E bioavailability.
• Bioconjugation & Protein PEGylation: Serving as a functionalized PEG derivative for modifying biomolecules to enhance their stability and circulatory half-life.
• Polymer & Material Science: As a macromolecular antioxidant additive to create oxidation-resistant polymers and coatings.
• Research & Development: As a key biochemical tool in academic and industrial R&D for studying antioxidant mechanisms and developing novel delivery platforms.

Basic Information

Product Name	Poly(Oxy-1,2-Ethanediyl),α-[4-[[3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl]Oxy]-1,4-Dioxobutyl]-ω-Methoxy-Polymer
CAS No.	1309573-60-1
Molecular Formula	Typically represented as (C2H4O)n•C38H64O5 (PEG-Vitamin E Succinate)
Molecular Weight	Variable, dependent on the PEG chain length (n). Contact for details.
Synonyms	Vitamin E TPGS (Tocopheryl Polyethylene Glycol Succinate) derivative; PEGylated Vitamin E Succinate; TPGS Polymer; α-Tocopherol polyethylene glycol succinate polymer; D-α-Tocopheryl PEG 1000 Succinate related polymer; Tocofersolan analog; Water-soluble Vitamin E polymer; Antioxidant PEG conjugate.
EINECS	Contact for details.

Quality Control

Our Poly(Oxy-1,2-Ethanediyl),α-[4-[[3,4-Dihydro-2,5,7,8-Tetramethyl-2-(4,8,12-Trimethyltridecyl)-2H-1-Benzopyran-6-Yl]Oxy]-1,4-Dioxobutyl]-ω-Methoxy-Polymer is manufactured under a strict quality management system. Each batch is tested to ensure identity, purity, and functional performance. Certificates of Analysis (COA) documenting key parameters such as assay, PEG chain length distribution, and residual solvents are available upon request. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical and cosmetic applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. For short-term use, storage at controlled room temperature (15-25°C) in a desiccator is acceptable. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (Vitamin E derivative content)
PEG Average Molecular Weight	As per grade (e.g., 1000, 1500 Daltons)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm
Peroxide Value	≤ 5.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.