Description

(3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methanol is a high-value, complex heterocyclic building block featuring a chlorotrifluoromethyl-substituted bipyridine core. This compound is critical for research and development in advanced organic synthesis, particularly in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical companies for its unique structural motifs that enable the exploration of new chemical space and the development of compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a core scaffold for designing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Biology Probe: Used in medicinal chemistry to study protein-ligand interactions and for hit-to-lead optimization in drug discovery programs.
• Material Science Research: Potential building block for advanced organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, functionalized bipyridine structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	(3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methanol
CAS No.	1308146-14-6
Molecular Formula	C13H14ClF3N2O
Molecular Weight	306.71 g/mol
Synonyms	4-Piperidinemethanol, 1-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]-; 1-(6-Chloro-5-(trifluoromethyl)pyridin-3-yl)piperidin-4-ylmethanol; (3'-Chloro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)methanol; 1-[6-Chloro-5-(trifluoromethyl)-3-pyridyl]piperidine-4-methanol; 1308146-14-6; 4-Piperidinemethanol, 1-[6-chloro-5-(trifluoromethyl)-3-pyridinyl]- (9CI)
EINECS	Contact for details

Quality Control

Our (3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material that meets the stringent requirements for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.