Description

(2E)-1-{4-[(4-Chlorobenzyl)Oxy]Phenyl}-3-(Dimethylamino)Prop-2-En-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its chalcone-based molecular structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within medicinal chemistry and process R&D. Our supply ensures consistent quality and reliable availability for global scale-up projects.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug molecules for various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Employed in the research and process development stages for creating new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Serves as a starting material for developing specialized probes to study biological mechanisms and target validation.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing complex, high-value organic molecules.

Basic Information

Product Name	(2E)-1-{4-[(4-Chlorobenzyl)Oxy]Phenyl}-3-(Dimethylamino)Prop-2-En-1-One
CAS No.	1306753-64-9
Molecular Formula	C18H18ClNO2
Molecular Weight	315.79 g/mol
Synonyms	(E)-1-(4-((4-Chlorobenzyl)oxy)phenyl)-3-(dimethylamino)prop-2-en-1-one; 1-[4-[(4-Chlorophenyl)methoxy]phenyl]-3-(dimethylamino)-2-propen-1-one; 4'-[(4-Chlorobenzyl)oxy]chalcone N,N-dimethylamine; 2-Propen-1-one, 1-[4-[(4-chlorophenyl)methoxy]phenyl]-3-(dimethylamino)-, (2E)-; (E)-3-(Dimethylamino)-1-[4-[(4-chlorobenzyl)oxy]phenyl]prop-2-en-1-one; 4-((4-Chlorobenzyl)oxy)chalcone dimethylamine derivative; N,N-Dimethylaminochalcone ether derivative
EINECS	Contact for details

Quality Control

Our (2E)-1-{4-[(4-Chlorobenzyl)Oxy]Phenyl}-3-(Dimethylamino)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.