Description

5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahy-Dro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine and a carboxylic acid functional group. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors.
• Organic Synthesis Reagent: Used in medicinal chemistry for constructing complex heterocyclic scaffolds and introducing the tert-butoxycarbonyl (Boc) protecting group.
• Research & Development: Essential material for lead optimization and structure-activity relationship (SAR) studies in academic and industrial labs.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial manufacturing of target APIs.
• Custom Synthesis: Basis for the preparation of more complex derivatives and analogs for biological screening.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahy-Dro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid
CAS No.	1306739-66-1
Molecular Formula	C14H21N3O4
Molecular Weight	295.34 g/mol
Synonyms	1-Methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid; 1-Methyl-5-Boc-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid; 5-Boc-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid; tert-Butyl 1-methyl-3-(carboxy)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylate; 1306739-66-1; Pyrazolopyridine-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonyl)-1-Methyl-4,5,6,7-Tetrahy-Dro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.