Description

2-(5-Fluoropyridin-3-Ylsulfonyl)Octahydropyrrolo[3,4-C]Pyrrole CAS NO 1306711-85-2 is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrrolidine-pyrrole core with a fluoropyridine sulfonyl substituent. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization in drug discovery programs.
• API Development: Integral in the development route of potential APIs that leverage the fluoropyridine and bicyclic amine pharmacophores for enhanced bioavailability and target binding.
• Preclinical & Clinical Trial Material: Supplied in GMP or high-purity grades for the production of materials required for non-clinical studies and early-phase clinical trials.
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects on behalf of pharmaceutical clients.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways in academic and industrial research settings.

Basic Information

Product Name	2-(5-Fluoropyridin-3-Ylsulfonyl)Octahydropyrrolo[3,4-C]Pyrrole
CAS No.	1306711-85-2
Molecular Formula	C11H14FN3O2S
Molecular Weight	271.31 g/mol
Synonyms	Octahydro-2-[(5-fluoro-3-pyridinyl)sulfonyl]pyrrolo[3,4-c]pyrrole; 2-((5-Fluoropyridin-3-yl)sulfonyl)octahydropyrrolo[3,4-c]pyrrole; 1,3,3a,4,6,6a-Hexahydro-2H-pyrrolo[3,4-c]pyrrole-2-carboxylic acid, 5-fluoro-3-pyridinesulfonyl ester; 1306711-85-2; 2-(5-Fluoropyridine-3-sulfonyl)octahydro-1H-pyrrolo[3,4-c]pyrrole; 5-Fluoro-3-((hexahydro-1H-pyrrolo[3,4-c]pyrrol-2(3H)-yl)sulfonyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(5-Fluoropyridin-3-Ylsulfonyl)Octahydropyrrolo[3,4-C]Pyrrole adheres to stringent quality protocols suitable for pharmaceutical development. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); ensure containers are sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.