Description

2-Amino-5-Chloro-4-Methylnicotinonitrile CAS NO 1305712-87-1 is a high-purity, functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and nitrile functional groups on a chlorinated pyridine core, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-5-Chloro-4-Methylnicotinonitrile
CAS No.	1305712-87-1
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	2-Amino-5-chloro-4-methylpyridine-3-carbonitrile; 5-Chloro-4-methyl-2-aminonicotinonitrile; 3-Cyano-5-chloro-4-methyl-2-aminopyridine; 2-Amino-5-chloro-4-methyl-3-cyanopyridine; 1305712-87-1; 2-Amino-5-chloro-4-methylnicotinonitrile; 5-Chloro-2-amino-4-methylnicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Chloro-4-Methylnicotinonitrile is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.