Description

n-(2-Chloro-6-Iodo-4-(Trimethylsilyl)-Pyridin-3-Yl)Pivalamide is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated and silylated pyridine core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable halogen and silyl functional groups.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides.
• Chemical Biology Probes: Employed in the creation of labeled compounds or probes for studying biological mechanisms.
• Process Chemistry Development: Used to scale up and optimize synthetic routes for active pharmaceutical ingredients (APIs).
• Material Science Research: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its aromatic and silyl components.

Basic Information

Product Name	n-(2-Chloro-6-Iodo-4-(Trimethylsilyl)-Pyridin-3-Yl)Pivalamide
CAS No.	1305325-24-9
Molecular Formula	C13H18ClIN2OSi
Molecular Weight	408.73 g/mol
Synonyms	Pivalamide, N-[2-chloro-6-iodo-4-(trimethylsilyl)-3-pyridinyl]-; 2-Chloro-6-iodo-4-(trimethylsilyl)pyridin-3-amine, N-pivaloyl derivative; 1305325-24-9; 3-Pivalamido-2-chloro-6-iodo-4-(trimethylsilyl)pyridine; N-(2-Chloro-6-iodo-4-trimethylsilylpyridin-3-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-6-Iodo-4-(Trimethylsilyl)-Pyridin-3-Yl)Pivalamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.