Description

5-Chloro-2,3-Dimethoxypyridin-4-Ol is a high-purity, multi-functional pyridine derivative serving as a critical pharmaceutical intermediate and organic synthesis building block. Its unique halogenated and methoxylated structure makes it a versatile precursor for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and functional polymers.
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes to study biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke organic synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Item	Detail
Product Name	5-Chloro-2,3-Dimethoxypyridin-4-Ol
CAS No.	1305325-20-5
Molecular Formula	C7H8ClNO3
Molecular Weight	189.60 g/mol
Synonyms	4-Hydroxy-5-chloro-2,3-dimethoxypyridine; 5-Chloro-2,3-dimethoxy-4-hydroxypyridine; 5-Chloro-4-hydroxy-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-chloro-4-pyridinol; 5-Chloro-2,3-dimethoxypyridin-4-ol; 4-Pyridinol, 5-chloro-2,3-dimethoxy-; 1305325-20-5
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2,3-Dimethoxypyridin-4-Ol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.